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Our clinical studies

We are committed to make our Clinical trials Information and Results accessible and transparent while maintaining participants privacy.

 

Clinical studies

This site provides information on both ongoing and completed clinical trials sponsored by Pierre Fabre since 2004. Real-world evidence studies which began after 01 January 2020 are also accessible.

 

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Current studies

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Dermatology

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Title Therapeutic area Phase Status Start date (Planned) End date

A randomised, controlled, multidose, multicentre, adaptive phase II/III study in infants with proliferating infantile hemangiomas requiring systemic therapy to compare four regimens of propranolol (1 or 3 mg/kg/day for 3 or 6 months) to placebo (double blind).

Dermatology Phase II Completed 24 February 2010 05 November 2013

Efficacy and tolerability of Chondroitin Sulphate 1000mg, twice daily in patients with symptomatic knee osteoarthritis

Rhumatology Phase III Completed 07 January 2010 04 July 2011

Exploratory study of besipirdine efficacy and safety in male patients with persistent stress urinary incontinence after radical prostatectomy

Urology Phase II Completed 14 December 2009 12 July 2010

Pharmacodynamic and clinical assessment of DC 982 GE (2,4 or 6 capsules per day) in patients with chronic venous disorders : randomised, placebo-controlled, dose effect, double blind, parallel group

Vascular Phase II Completed 07 December 2009 09 November 2010

A dose-finding study of efficacy and safety of F13640 in patients with moderate to severe painful peripheral diabetic polyneuropathy

Central Nervous System Phase II Completed 27 October 2009 09 December 2010

Effects of OMACOR in patients with a cardiac sodium channel gene SCN5A mutation, one variant of the congenital long-QT syndrome. A proof of concept study

Cardiovascular Phase II Completed 07 October 2009 25 May 2010

Prospective randomised phase II trial of oral vinorelbine and cisplatin or pemetrexed and cisplatin in first line Metastatic or Locally Advanced Non-Small-Cell Lung Cancer patients with non-squamous histological type

Oncology Phase II Completed 04 September 2009 17 September 2012

Phase III trial of IV vinflunine versus an alkylating agent in patients with metastatic breast cancer previously treated with or resistant to an anthracycline, a taxane, an antimetabolite, and a vinca-alkaloid (study L00070 IN 308 B0)

Oncology Phase III Completed 01 July 2009 30 January 2014

A phase III trial of vinflunine + capecitabine versus capecitabine alone in patients with advanced breast cancer previously treated with or resistant to an anthracycline and who are taxane resistant

Oncology Phase III Completed 06 May 2009 18 September 2015

Non inferiority study of a malathion 0.5% lotion versus reference therapy in the treatment of head lice: multicentre, randomised, investigator masked, parallel group

Parasite Phase III Completed 24 November 2008 02 November 2009

A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a sequential therapy with RV4104A ointment, ciclopiroxolamine cream and ciclopirox film-forming solution compared with amorolfine nail lacquer alone for the treatment of dermatophytic onychomycosis (toenail) without matrix involvement

Dermatology Phase IV Completed 10 November 2008 29 August 2011

Impact of the V0034CR 01B emollient on atopic dermatitis symptoms in children. A randomised, placebo-controlled, parallel-groups, double-blind study

Dermatology Phase IV Completed 30 October 2008 23 May 2009

Etude de l'efficacité de CIRKALM crème versus placebo dans le traitement des douleurs anales

Other Phase IV Completed 28 October 2008 10 December 2009

Evaluation du pouvoir bactériostatique de la préparation V0079CR CETAVLON sur la flore cutanée au niveau des mains. Etude preuve de concept.

Other Phase IV Completed 01 October 2008 01 November 2008

Comparative study of efficacy and safety of Structum® and Chondrosulf® in patients with symptomatic osteoarthritis of the knee.A Multicenter, Randomized, Double-Blind, Double Placebo-Controlled, Parallel Group Study

Rhumatology Phase IV Completed 15 September 2008 17 June 2009

Comparative study of the effect of 4-week treatment with ossein-hydroxyapatite compound versus calcium carbonate on bone biomarkers in young women with low calcium intake. Prospective, monocenter, randomized, open-label, two-period,cross-over trial

Rhumatology Phase IV Completed 09 September 2008 13 January 2009

Reduction of the gingival inflammation by V0109 DI. Randomised, parallel groups, double blind study, V0109 DI versus placebo, in patients presenting gingivitis

dental Phase III Completed 27 August 2008 12 December 2008

Clinical trial of the efficacy and tolerability of an immunostimulant drug, composed by ribosomal fractions, in socialized paediatric patients in order to prevent recurrent respiratory infections

Respiratory Phase IV Completed 25 August 2008 14 December 2009

Evaluation of the effect of 6 months treatment with DC158AM on fatigue in patients with Parkinson's disease. Multicentre, randomised, double-blind, placebo-controlled study in parallel groups

Mental Health Phase IV Completed 07 August 2008 02 July 2010

Effects of TANGANIL (three 500 mg tablets twice daily) on postural disturbances in the elderly

Central Nervous System Phase II Completed 11 June 2008 14 October 2008

Get access to Partner's pivotal studies supporting our authorized drugs in Europe

Results from pivotal studies conducted by our partners and supporting a marketing approval for whom Pierre Fabre is the holder in Europe are shared below:

 

Melanoma

SPONSOR: PFIZER

Breast cancer 

SPONSOR: PUMA BIOTECHNOLOGY

Colorectal cancer

SPONSOR: PFIZER

Post-transplantation lymphoproliferative disease EBV+

SPONSOR: ATARA