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Our clinical studies

We are committed to make our Clinical trials Information and Results accessible and transparent while maintaining participants privacy.

 

Clinical studies

This site provides information on both ongoing and completed clinical trials sponsored by Pierre Fabre since 2004. Real-world evidence studies which began after 01 January 2020 are also accessible.

 

Total studies

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Current studies

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Oncology

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Dermatology

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Title Therapeutic area Phase Status Start date (Planned) End date

A multicenter, randomized, open-label, 2-arm, Phase II trial with a safety lead-in phase evaluating the combination of encorafenib and cetuximab versus irinotecan/cetuximab or infusional 5-fluorouracil (5-FU)/folinic acid (FA)/irinotecan (FOLFIRI)/cetuximab in Chinese patients with BRAFV600E mutant metastatic colorectal cancer.

Oncology Phase II Active 02 September 2021 September 2024

Study of FIH of STX-241 in locally advanced or metastatic NSCLC resistant to EGFR TKIs (STX-241FIH)

Oncology Phase I / II Active 17 September 2024 July 2030

Multicenter, Open-label, Phase II Study with a Safety Lead-in part Investigating the Efficacy, Safety and Pharmacokinetics of Encorafenib and Binimetinib Combination in BRAFV600E mutated Chinese Patients with Metastatic Non-Small Cell Lung Cancer who are BRAF- and MEK inhibitor treatment-naïve

Oncology Phase II Active not recruiting 27 May 2024 April 2026

Natural History and Disease Burden of X-linked Hypohidrotic Ectodermal Dysplasia (XLHED): An Observational, Multicentre, International Study

Dermatology RWE Active not recruiting July 2023 September 2026

A Nerlyfe ancillary study to describe recurrence in breast cancer patients treated with neratinib in a real-world setting

Oncology RWE Active not recruiting 08 May 2022

Multicentre, multi-country, prospective, observational, post-authorisation safety study to describe the incidence of discontinuation due to diarrhoea within the first 3 months of treatment with neratinib, in adult breast cancer patients treated in extended adjuvant in a real-world setting: the NERLYFE study..

Oncology RWE Active not recruiting 08 May 2022 January 2026

Study of the combination of Binimetinib and Encorafenib in adolescent patients with unresectable or Metastatic BRAF V600-mutant Melanoma

Oncology Phase I Active not recruiting 03 August 2020 05 September 2025

Efficacy and safety of 8% Clobetasol nail lacquer formulation versus vehicle in nail psoriasis

Dermatology Phase II Completed 2006 12 November 2007

Clinical trial of the efficacy and tolerability of an immunostimulant drug, composed by ribosomal fractions, in socialized paediatric patients in order to prevent recurrent respiratory infections

Respiratory Phase IV Completed 25 August 2008 14 December 2009

Post-operative care by chlorhexidine mouthwash after periodontal surgery. Randomised, parallel groups; blind study, DC071BB versus placebo, in patients presenting with periodontal surgery with suture

dental Phase IV Completed 23 November 2005 03 June 2006

Phase III trial of IV vinflunine versus an alkylating agent in patients with metastatic breast cancer previously treated with or resistant to an anthracycline, a taxane, an antimetabolite, and a vinca-alkaloid (study L00070 IN 308 B0)

Oncology Phase III Completed 01 July 2009 30 January 2014

Efficacy and tolerance of the emollient cream V0034 CR in the symptomatic treatment of ichthyosis in children. International, multicentric, randomised, controlled, double blind study, in parallel group

Dermatology Phase III Completed 05 February 2007 01 November 2007

V0251 oral suspension efficacy and tolerance in vestibular neuritis. A randomised double-blind placebo controlled study

Central Nervous System Phase II Completed 17 May 2011 30 April 2012

Encorafenib in combination with Cetuximab in BRAFV600E–Mutated Metastatic Colorectal Cancer: A European pooled analysis of observational studies

Oncology RWE Completed 01 January 2020 31 October 2024

A dose-finding study of efficacy and safety of F13640 in patients with moderate to severe painful peripheral diabetic polyneuropathy

Central Nervous System Phase II Completed 27 October 2009 09 December 2010

Evaluation du pouvoir bactériostatique de la préparation V0079CR CETAVLON sur la flore cutanée au niveau des mains. Etude preuve de concept.

Other Phase IV Completed 01 October 2008 01 November 2008

Efficacy and tolerance of V0071 GM 01A in inflammatory seborrhoeic dermatitis of the scalp.

Dermatology Phase II Completed 2007 23 January 2009

Comparative study of efficacy and safety of Structum® and Chondrosulf® in patients with symptomatic osteoarthritis of the knee.A Multicenter, Randomized, Double-Blind, Double Placebo-Controlled, Parallel Group Study

Rhumatology Phase IV Completed 15 September 2008 17 June 2009

Proof of Concept study of the efficacy and tolerability of a 4-week treatment with F13640 in patients in whom the adaptation of opioid therapy of cancer pain has failed. A prospective, multinational, multicentre, randomised, double-blind, placebo-controlled study.

Central Nervous System Phase II Completed 20 March 2008 03 November 2008

Prospective randomised phase II trial of oral vinorelbine and cisplatin or pemetrexed and cisplatin in first line Metastatic or Locally Advanced Non-Small-Cell Lung Cancer patients with non-squamous histological type

Oncology Phase II Completed 04 September 2009 17 September 2012

Get access to Partner's pivotal studies supporting our authorized drugs in Europe

Results from pivotal studies conducted by our partners and supporting a marketing approval for whom Pierre Fabre is the holder in Europe are shared below:

 

Melanoma

SPONSOR: PFIZER

Breast cancer 

SPONSOR: PUMA BIOTECHNOLOGY

Colorectal cancer

SPONSOR: PFIZER

Post-transplantation lymphoproliferative disease EBV+

SPONSOR: ATARA