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Our clinical studies

We are committed to make our Clinical trials Information and Results accessible and transparent while maintaining participants privacy.

 

Clinical studies

This site provides information on both ongoing and completed clinical trials sponsored by Pierre Fabre since 2004. Real-world evidence studies which began after 01 January 2020 are also accessible.

 

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Current studies

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Oncology

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Dermatology

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Rare diseases

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Title Therapeutic area Phase Status Start date (Planned) End date

Non inferiority study of a malathion 0.5% lotion versus reference therapy in the treatment of head lice: multicentre, randomised, investigator masked, parallel group

Parasite Phase III Completed November 24, 2008 November 02, 2009

Assessment of the efficacy of a new formulation of minoxidil (DC120) on hair growth, in a minizone model in androgenetic alopecia in men.

Dermatology Phase II Completed August 21, 2015 April 28, 2016

Effects of TANGANIL (three 500 mg tablets twice daily) on postural disturbances in the elderly

Central Nervous System Phase II Completed June 11, 2008 October 14, 2008

An open label, multicentre, phase I study to evaluate the impact of moderate and severe hepatic impairments on the pharmacokinetics and safety of encorafenib in combination with binimetinib in adult patients with unresectable or metastatic BRAF V600-mutant solid tumors.

Oncology Phase I Completed May 30, 2022 January 10, 2023

A Randomized, single-center, open-label, single dose, two-period, crossover study to investigate the relative bioavailability of Binimetinib 3 x15 mg and 45 mg tablets in healthy participants

Oncology Phase I Completed September 03, 2021 June 18, 2023

Etude de l'efficacité de CIRKALM crème versus placebo dans le traitement des douleurs anales

Other Phase IV Completed October 28, 2008 December 10, 2009

A Randomised Phase II study of Oral Vinorelbine or I.V. Vinorelbine in patients with metastatic breast cancer previously treated with anthracyclines

Oncology Phase II Completed September 30, 2004 June 01, 2007

Clinical and biophysics evaluation of the cutaneous modifications following the local use of a lotion containing 0,1 % of trétinoïne

Dermatology Phase IV Completed February 2013 February 20, 2014

Bronchodilator properties and safety of a repeated dose of V0162 inhalation powder in asthma

Respiratory Phase II Completed September 26, 2013 April 30, 2014

PERMIXON® 160 mg hard capsule versus placebo in the treatment n the treatment of symptomatic lower urinary tract symptoms due to benign prostatic hyperplasia

Urology Phase IV Completed May 07, 2014 June 27, 2016

Phase III study of IV vinflunine in combination with methotrexate versus methotrexate alone in patients with recurrent or metastatic squamous cell carcinoma of the head and neck previously treated with platinum-based chemotherapy (study L00070 IN 309 F0)

Oncology Phase III Completed April 02, 2012 November 23, 2018

Efficacy and safety of 0,1%, 0,5% and 1% TAZAROTENE nail lacquer formulation versus vehicle in nail psoriasis. International, multicenter, double-blind, randomized study of four parallel groups

Dermatology Phase II Completed April 28, 2005 May 08, 2006

Efficacy and safety assessment of 6 months (24 weeks) treatment with Structum® 500 mg capsule bid in hip osteoarthritis: multicenter randomised double blind parallel group and placebo controlled study

Rhumatology Phase IV Completed November 17, 2005 November 07, 2006

Treat study : treatment of iron deficiency anaemia with Tardyferon. Importance of prolonging iron supplementation in anemic women of childbearing age

Blood Disorders Phase IV Completed March 24, 2007 July 08, 2009

Etude en double aveugle versus placebo de l'efficacité et de la tolérance de Cirkan® sur la symptomatologie fonctionnelle veineuse éprouvée (C0s à C3s) par les patientes obèses

Cardiovascular Phase IV Completed June 01, 2007 December 13, 2007

Ensayo clínico en fase I-II de vinorelbina oral (Navelbine) en combinación con capecitabina en tratamiento de primera línea en pacientes con cáncer de mama avanzado

Oncology Phase I Completed September 28, 2004 October 14, 2009

Effect of V0251 in acute vertigo. A randomized double blind placebo conrolled study

Central Nervous System Phase II Completed June 16, 2012 April 15, 2013

Clinical efficacy and safety of J022X ST in the prevention of Recurrent Upper-Respiratory Tract Infections (RURTI) in children with a high risk of recurrence

Respiratory Phase III Completed September 02, 2013 October 17, 2016

Pharmacodynamic and clinical assessment of DC 982 GE (2,4 or 6 capsules per day) in patients with chronic venous disorders : randomised, placebo-controlled, dose effect, double blind, parallel group

Vascular Phase II Completed December 07, 2009 November 09, 2010

Phase III study of vinflunine plus gemcitabine versus paclitaxel plus gemcitabine in patients with unresectable, locally recurrent or metastatic breast cancer after prior anthracycline-based adjuvant chemotherapy

Oncology Phase III Completed June 27, 2006 February 25, 2015

Get access to Partner's pivotal studies supporting our authorized drugs in Europe

Results from pivotal studies conducted by our partners and supporting a marketing approval for whom Pierre Fabre is the holder in Europe are shared below:

 

Melanoma

SPONSOR: PFIZER

Breast cancer 

SPONSOR: PUMA BIOTECHNOLOGY

Colorectal cancer

SPONSOR: PFIZER

Post-transplantation lymphoproliferative disease EBV+

SPONSOR: ATARA